Medications Used for Common Gastrointestinal Conditions:

Acid Reducing Medications

These medications are mainly used for gastroesophageal reflux disease/ heartburn, and treatment/prevention of ulcers.

Start working immediately and are inexpensive but are effective for only a short time.
  • Maalox
  • Mylanta, etc.
H-2 blockers
Last much longer than antacids and are often quite effective.
  • cimetidine (Tagamet)
  • ranitidine (Zantac)
  • famotidine (Pepcid)
Proton Pump Inhibitors
Are the most potent of acid blockers and last the longest. Patients with esophagitis (inflammation of the esophagus) due to reflux should, generally, be on one of these medications.
  • omeprazole (Prilosec)
  • lansoprazole (Prevacid)
  • esomeprazole (Nexium)
  • pantoprazole (Protonix)
  • rabeprazole (Aciphex)

Anti-anxiety and anti-depressant medications may be helpful in some patients with Irritable Bowel Syndrome (IBS)

  • amitriptyline (Elavil)
  • Triavil

Anti-diarrheal medications
Should be used sparingly. Any use beyond the package recommendations should be discussed with a doctor.

  • Loperamide (Immodium)
  • diphenoxylate + atropine (Lomotil)
  • cholestyramine
  • Donnatol
  • attapulgite (Kaopectate)

Antiemetics (anti-nausea medications)

  • prochlorperazine (Compazine)
  • promethazine (Phenergan)
  • metoclopramide (Reglan)
  • trimethobenzamide (Tigan)
  • ondansetron (Zofran)
  • granisetron (Kytril)

Fiber Supplements
Provide bulk to the stool.
They can be used to treat both constipation and diarrhea and may be helpful in many gastrointestinal problems.

  • psyllium (Metamucil)
  • methylcellulose (Citrucel)
  • polycarbophil (Fibercon)


  • bisacodyl (Dulcolax, Correctol)
  • cascara
  • castor oil
  • Docusate (Colace) a stool softener
  • CoLyte
  • GoLytely
  • lactulose
  • magnesium citrate
  • Miralax
  • Milk of Magnesia
  • senna
  • sodium phosphate
  • Visicol (tablet form of sodium phosphate)